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For more information about any current, patient enrolling prospective studies produced in collaboration with Excelen, or if you have interest in pursuing other orthopaedic clinical research at Hennepin County Medical Center, please contact Joan E. Bechtold at bechtold@umn.edu, Dr. Andrew Schmidt at schmi115@umn.edu, J.R. Westberg at Jerald.westberg@hcmed.org, Claudia Miller at Claudia.miller@hcmed.org or Barbara Wicklund at bwicklund@excelen.org.
Patients with tibial shaft fractures requiring surgical intervention A multi-center randomized clinical trial to determine if the removal of interstitial fluid by the Twin Star Catheter can lower muscle compartment pressure and thereby reducing the need for surgical fasciotomy. Industry and NIH and US Army sponsored.
Patients with a Gustilo-Anderson Type II or III open fracture of the upper or lower extremity are being enrolled in a tandem center study with the Mayo Clinic comparing results for open fractures receiving adjunctive localized wound antimicrobial therapy via either antibiotic-impregnated polymethylmethacrylate (PMMA) beads or silver impregnated Vacuum Assisted Closure (V.A.C.) sponge.
Adult patients with isolated femur fractures undergoing femoral intramedullary nailing are being enrolled in a randomized clinical trial comparing the Synthes Reamer Irrigator Aspirator (RIA) to conventional intramedullary reamers, measuring both marrow embolism by trans-esophageal echocardiography and activation of the systemic inflammatory response syndrome as indicated by IL-6 levels. Industry sponsored.
Adult patients with distal femur fractures are being enrolled in a multi-center randomized clinical trial comparing intramedullary nailing and plate fixation in distal femur fractures. Sponsored by the Orthopaedic Trauma Association.
Adult patients with proximal tibia fractures are being enrolled in a multi-center randomized clinical trial comparing intramedullary nailing and plate fixation in proximal tibia fractures. Sponsored by the Orthopaedic Trauma Association.
Adult patients with a scapula fracture are being enrolled in a multi-center study group evaluating the outcomes of patients with extra-articular scapula fractures.
Adult patients with a mid-shaft tibia fracture requiring intramedullary nailing are being enrolled in a phase I clinical trial of a novel growth factor in adult patients with a closed tibia shaft fracture undergoing intramedullary nailing. Industry sponsored.
Adult patients with displaced lateral malleolus fractures are being enrolled in a multicenter randomized trial comparing lateral and antiglide plating in displaced lateral malleolus fractures.
Adult men or women, age > 50, with femoral neck fractures requiring open reduction internal fixation are being enrolled in a multi-center randomized trial comparing sliding hip screws and cancellous screws on revision surgery rates and quality of life in the treatment of femoral neck fractures. Sponsored by the National Institute of Health.
Adult patients with unilateral sacral fractures are being enrolled in a multicenter study evaluating the patient-based and radiographic outcomes of sacral fractures based on injury pattern, fracture displacement, and treatment method.
A series of charts and radiographs from past patients treated with hybrid plates with varying screw fixation methods for proximal humerus, distal femur, and proximal tibia fractures are being reviewed with regards to outcome.
A retrospective review of tibia plateau fractures is being undertaken to propose an updated classification of these fractures that takes into account modern concepts of their treatment.
A retrospective review, with possible clinical follow up, of operative and non-operative multiple metatarsal fractures is being undertaken to better classify indication and treatment methods for such fractures.
A retrospective review of our experiences with the treatment of acute clavicle fractures in order to support or refute the claim that the 3.5 mm Recon Plate provides insufficient biomechanical stability in the treatment of clavicle fractures.
A retrospective chart review to assess VTE risk in orthopaedic patients. Excelen is inititiating a protocol to have this score determined at the time of each patient’s admission in order to standardize care. Obtaining retrospective data of patients that developed DVT will help to validate the accuracy of this score. The validation of this score may also help support a future clinical study.
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